May 29, 2025

Measuring the ROI of Pharmacy Benefit Programs

 

Pharmacy benefit programs can be powerful tools to control rising costs and improve outcomes—but not all programs are created equal. With pharmacy spend now accounting for nearly 30% of total benefit costs, CFOs and CHROs are under pressure to make smarter, more strategic decisions. Yet too often, plan sponsors are presented with programs that promise savings without transparent data to back them up. Before you greenlight any new initiative, make sure you’re asking the right questions to ensure alignment with your goals, financial accountability and a positive employee experience.

 

5 Key Questions on PBM Programs

Pharmacy benefit programs can help plan sponsors enhance cost efficiency, performance and plan member outcomes. However, their complexity can present challenges for plan sponsors. Accurately evaluating their return on investment (ROI) requires specialized expertise in financial, clinical and strategic analysis.

Ask your pharmacy benefit manager (PBM) these key questions to determine if a program will align with your plan’s goals:

  • What is the potential cost savings of the program versus member disruption? What will it take for plan members to participate?
    • Ideally, you want programs that will provide high cost savings and low member disruption.
  • Can my plan opt out of the program? If so, what does this involve? What is the fee?
  • How do you measure the ROI of the program? How will outcomes be reported? What have been the outcomes of the program on other plans?
  • What is the member experience? Can members opt out?
  • Does the plan have to sign a contract amendment or implementation document?

 

The Takeaway

Evaluating pharmacy programs shouldn’t be a leap of faith. These five questions can help clarify whether a new program will truly deliver value—or simply add administrative burden and member dissatisfaction. In a pharmacy benefits landscape where transparency and cost control are more critical than ever, understanding the true ROI of pharmacy initiatives is a strategic imperative.

If you’re unsure whether your current or proposed programs are delivering measurable results, let’s talk. We help organizations cut through the complexity and design pharmacy strategies that work—for your bottom line and your people.